Product Description

🔹 Product Overview

Estofert 2 mg Tablet is an oral estrogen medicine containing Estradiol 2 mg. It is manufactured/marketed by Gufic Biosciences Ltd. and is used as hormone replacement therapy (HRT) for estrogen deficiency, particularly for managing menopausal symptoms. It may also be prescribed in selected patients for prevention of postmenopausal bone loss.

🔹 Composition
Active ingredient: Estradiol – 2 mg
Dosage form: Oral tablet
Strength: 2 mg
Therapeutic class: Estrogen / Hormone Replacement Therapy
Manufacturer/Marketer: Gufic Biosciences Ltd.
🔹 Uses & Indications
Hormone replacement therapy for menopausal symptoms
Relief of:
Hot flushes
Night sweats
Vaginal dryness
Vaginal itching and discomfort
Treatment of estrogen deficiency
Estrogen replacement in selected cases of ovarian failure or reduced ovarian estrogen production
Prevention of osteoporosis in selected postmenopausal women at increased risk of bone loss, when HRT is appropriate.
🔹 How It Works

Estofert contains estradiol, a form of estrogen that replaces or supplements estrogen normally produced by the body. Estradiol binds to estrogen receptors and influences estrogen-responsive tissues, helping reduce symptoms caused by declining estrogen levels and supporting maintenance of bone density.

🔹 Key Benefits
Helps relieve common menopausal symptoms
Replaces deficient estrogen
Helps reduce vaginal dryness and related discomfort
Supports maintenance of bone density in appropriate postmenopausal patients
Convenient oral 2 mg tablet formulation
🔹 Dosage & Administration

Take Estofert 2 mg exactly as prescribed by the healthcare professional. The tablet should be swallowed whole with water and may generally be taken with or without food. Take it at approximately the same time each day. The dose and duration depend on the indication, age, medical history, and individual response. Do not change the dose or discontinue HRT without medical advice.

🔹 Possible Side Effects
Headache
Breast tenderness or breast pain
Irregular vaginal bleeding or spotting
Abdominal cramps or bloating
Nausea
Vomiting
Hair loss
Fluid retention

Seek medical attention for unusual vaginal bleeding, breast changes, chest pain, shortness of breath, severe headache, or painful swelling of a leg, as these may require urgent assessment.

🔹 Precautions & Warnings
Prescription medicine — use only under medical supervision.
Do not use in pregnancy unless specifically directed by a specialist.
Inform the doctor about any history of blood clots, stroke, heart disease, liver disease, or estrogen-dependent cancer.
Unexplained vaginal bleeding should be investigated before starting estrogen therapy.
Systemic estrogen therapy can increase the risk of certain blood clots, stroke, and hormone-sensitive cancers, depending on the patient's age, treatment duration, and whether a progestogen is also required.
Women with an intact uterus generally require appropriate progestogen protection when systemic estrogen is used long term, to reduce the risk of endometrial hyperplasia/cancer.
Tell the doctor about all medicines and supplements being taken.
Regular medical follow-up is recommended during long-term HRT.
🔹 Storage

Store Estofert 2 mg tablets in their original packaging, protected from excessive heat, moisture, and direct sunlight. Current product information specifies storage below 30 c