PANGRAF 2MG TAB contains Tacrolimus 2 mg. It is an immunosuppressant medicine used to reduce the activity of the immune system. It is commonly prescribed to help prevent organ rejection after organ transplantation under specialist medical supervision.
🔹 Key Uses
Prevention of organ rejection after kidney transplantation
Prevention of organ rejection after liver transplantation
Prevention of organ rejection after heart transplantation
Prevention of organ rejection after other selected organ transplants
Used with other immunosuppressive medicines as prescribed by a transplant specialist
🔹 Composition
Tacrolimus 2 mg
🔹 How It Works
Tacrolimus suppresses certain immune system cells by inhibiting calcineurin activity. This reduces the production of immune signals that can cause the body to attack and reject a transplanted organ.
🔹 Key Benefits
Helps prevent organ rejection
Suppresses excessive immune system activity
Supports long term transplant management
Helps maintain transplanted organ function when used as prescribed
🔹 Dosage and Administration
Take PANGRAF 2MG TAB exactly as prescribed by the transplant specialist. The dose is individualized according to the transplanted organ, blood tacrolimus levels, kidney and liver function, other medicines and clinical response. Take it at the same time each day and do not stop or change the dose without medical advice. Regular blood tests are required to monitor tacrolimus levels and organ function.
🔹 Possible Side Effects
Headache
Tremors
High blood pressure
Increased blood sugar
Nausea or diarrhea
Kidney function changes
Increased risk of infections
Electrolyte disturbances
🔹 Precautions and Warnings
Tacrolimus can significantly suppress the immune system and may increase the risk of serious infections and certain cancers. Regular monitoring of tacrolimus blood levels, kidney function, blood pressure, blood sugar and electrolytes is important. Inform the doctor about all medicines, supplements and herbal products being used because many medicines can affect tacrolimus levels. Avoid grapefruit and grapefruit juice unless specifically permitted by the doctor. Do not stop treatment suddenly, as this may increase the risk of organ rejection. Seek medical attention for signs of serious infection, unusual bleeding, severe weakness or significant changes in urine output.
Important: Always follow your healthcare provider's instructions when using this medication.
Note: This is general guidance. For specific instructions, please consult your healthcare provider or refer to the package insert.
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