🔹 Product Overview
Avicrest 2.5 gm Injection is a prescription advanced antibiotic medicine used for the treatment of serious bacterial infections, especially those caused by resistant Gram-negative bacteria. It contains a combination of Ceftazidime 2000 mg + Avibactam 500 mg, which works together to fight bacterial infections and overcome certain antibiotic resistance mechanisms.
Avicrest 2.5 gm Injection is generally used in hospital settings for complicated infections involving the urinary tract, respiratory tract, abdomen, and bloodstream, under the supervision of a qualified healthcare professional.
🔹 Key Uses
Treatment of complicated bacterial infections
Management of complicated urinary tract infections (cUTI)
Treatment of hospital-acquired and ventilator-associated bacterial pneumonia when indicated
Management of complicated intra-abdominal infections
Used for infections caused by certain resistant Gram-negative bacteria
Helps treat infections requiring advanced antibiotic therapy under specialist supervision
🔹 Composition
Active Ingredients:
Ceftazidime 2000 mg
Avibactam 500 mg
Dosage Form: Intravenous Injection
Drug Class: Cephalosporin antibiotic + Beta-lactamase inhibitor
Therapeutic Category: Advanced antibacterial medicine / Reserve antibiotic therapy
🔹 How It Works
Avicrest 2.5 gm Injection contains two components with complementary actions:
Ceftazidime blocks bacterial cell wall formation, causing bacterial death.
Avibactam inhibits certain bacterial beta-lactamase enzymes that can make bacteria resistant to antibiotics, thereby restoring the effectiveness of ceftazidime against susceptible bacteria.
🔹 Key Benefits
Provides effective antibiotic coverage for complicated infections
Helps manage infections caused by certain drug-resistant bacteria
Combines antibacterial action with resistance protection
Useful option in hospital-based antibiotic treatment plans
Injectable formulation allows controlled administration in severe infections
🔹 Dosage and Administration
Avicrest 2.5 gm Injection should be administered only by a healthcare professional
Usually given by intravenous infusion as prescribed by a doctor
Dose and duration depend on infection severity, kidney function, and patient condition
Kidney function monitoring may be required during treatment
Complete the prescribed antibiotic course as directed by the physician
🔹 Possible Side Effects
Common side effects may include:
Nausea
Vomiting
Diarrhea
Headache
Injection site reactions
Increased liver enzymes
Allergic reactions such as rash or itching
Seek immediate medical attention for severe allergic reactions, breathing difficulty, or serious symptoms.
🔹 Precautions
Use only under medical supervision
Inform your doctor about previous allergies to cephalosporins, penicillins, or other antibiotics
Dose adjustment may be required in patients with kidney problems
Inform your doctor about all medicines and supplements being taken
Avoid unnecessary antibiotic use to reduce antibiotic resistance
Complete the prescribed treatment duration even if symptoms improve
Important: Always follow your healthcare provider's instructions when using this medication.
Note: This is general guidance. For specific instructions, please consult your healthcare provider or refer to the package insert.
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