Product Description

🔹 Product Overview
IRNOTOP 40 mg Injection contains Irinotecan 40 mg, an anticancer medicine belonging to the topoisomerase I inhibitor class. It is a prescription chemotherapy medicine used primarily in the treatment of cancer of the colon and rectum, often as part of a combination chemotherapy regimen.

🔹 Key Uses
Treatment of colorectal cancer
Used in the management of cancer of the colon
Used in the management of cancer of the rectum
May be used in combination with other anticancer medicines for advanced or metastatic colorectal cancer
Helps slow the growth and multiplication of cancer cells

🔹 Composition
Active ingredient: Irinotecan 40 mg
Drug class: Topoisomerase I inhibitor
Therapeutic category: Antineoplastic / chemotherapy medicine
Dosage form: Injection
Route: Intravenous infusion
Prescription status: Prescription medicine

🔹 How It Works
Irinotecan works by inhibiting an enzyme called topoisomerase I, which cancer cells require for DNA replication and cell division. By interfering with this process, irinotecan damages cancer-cell DNA and helps slow or stop the growth of cancer cells.

🔹 Key Benefits
Helps control the growth of colorectal cancer cells
Used as part of chemotherapy treatment for colon and rectal cancers
Can be incorporated into combination chemotherapy regimens for advanced or metastatic colorectal cancer
Helps inhibit cancer-cell multiplication by interfering with DNA replication
Provides an established chemotherapy option for appropriate patients with colorectal cancer

🔹 Dosage and Administration
IRNOTOP 40 mg Injection must be administered only by a qualified healthcare professional, usually through an intravenous infusion. The dose and treatment schedule are individualized according to the cancer being treated, treatment regimen, body-surface area, blood counts, liver function, and overall health.
The 40 mg strength refers to the amount of irinotecan in the vial; it does not represent a standard single dose for every patient. Do not self-administer or alter the chemotherapy schedule.

🔹 Possible Side Effects
Possible adverse effects include:
Diarrhea
Nausea and vomiting
Fatigue
Weakness
Loss of appetite
Hair loss
Fever
Anemia
Reduced white blood cell count/neutropenia
Abdominal discomfort
Inflammation of the mucous membranes

🔹 Precautions
Before treatment, inform the treating oncologist about:
Liver or kidney problems
Previous chemotherapy reactions
Existing infections
All prescription and non-prescription medicines
Pregnancy or plans to become pregnant
Breastfeeding