🔹 Product Overview
GLIOZ 20 mg Capsule contains Temozolomide 20 mg, an oral anticancer medicine belonging to the alkylating agent class. It is a prescription chemotherapy medicine used for certain types of malignant brain tumors, including glioblastoma and anaplastic astrocytoma. Depending on the cancer and treatment plan, temozolomide may be used alongside radiotherapy or as subsequent chemotherapy. (1mg.com)
🔹 Key Uses
Treatment of certain malignant brain tumors
Used in newly diagnosed glioblastoma as part of an appropriate treatment regimen
Used for anaplastic astrocytoma that has returned or progressed after standard treatment
May be used with radiotherapy in selected patients
May be prescribed as maintenance chemotherapy according to the oncologist's treatment protocol
🔹 Composition
Active ingredient: Temozolomide 20 mg
Drug class: Alkylating agent
Therapeutic category: Antineoplastic / chemotherapy medicine
Dosage form: Capsule
Route: Oral
Marketer: Dr. Reddy's Laboratories Ltd. (1mg.com)
🔹 How It Works
Temozolomide is converted in the body into an active compound that chemically modifies DNA in cancer cells. This DNA damage interferes with cancer-cell replication and division, helping slow or stop the growth of susceptible tumor cells. (1mg.com)
🔹 Key Benefits
Helps slow the growth of certain malignant brain tumors
Targets rapidly dividing cancer cells by damaging their DNA
Provides an oral chemotherapy option for appropriate patients
Can be incorporated into combination treatment with radiotherapy when prescribed
Can be used in subsequent treatment cycles according to an individualized oncology protocol
🔹 Dosage and Administration
The dose and treatment schedule of GLIOZ 20 mg are determined by the treating oncologist according to the type of tumor, treatment stage, body-surface area, blood counts, previous treatment, and overall health.
Temozolomide is commonly administered in treatment cycles, and the prescribed dose may vary between patients. Do not change the dose, treatment days, or cycle schedule without your oncologist's instructions.
The capsule should be swallowed whole with water. It is commonly taken on an empty stomach and at approximately the same time on scheduled treatment days. Follow the specific instructions provided by your oncology team. (1mg.com)
🔹 Possible Side Effects
Possible side effects include:
Nausea
Vomiting
Constipation
Headache
Fatigue or weakness
Loss of appetite
Diarrhea
Dizziness
Hair loss
Fever
Low blood-cell counts
Increased susceptibility to infections
Because temozolomide can reduce blood-cell counts, regular blood tests are generally required during treatment. (1mg.com)
🔹 Precautions
GLIOZ 20 mg should be used only under the supervision of an oncologist.
Tell your doctor if you have:
Liver or kidney problems
Low blood-cell counts
A history of serious infections
Bleeding problems
Allergies to temozolomide or dacarbazine
Any other medical conditions
Any medicines or supplements you are currently taking
Important: Always follow your healthcare provider's instructions when using this medication.
Note: This is general guidance. For specific instructions, please consult your healthcare provider or refer to the package insert.
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